PREFACE
PART 1: CONCEPTS
A Brief Introduction to Traditional Bioconjugate Chemistry
[3+2] Dipolar Cycloadditions in Bioconjugation
Diels-Alder and Inverse Diels-Alder Reactions
The Staudinger Ligation
Thiol-Ene Chemistry
Ligand-Directed Tosyl and Acyl Imidazole Chemistry
Bioorthogonal Labeling of...
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PREFACE
PART 1: CONCEPTS
A Brief Introduction to Traditional Bioconjugate Chemistry
[3+2] Dipolar Cycloadditions in Bioconjugation
Diels-Alder and Inverse Diels-Alder Reactions
The Staudinger Ligation
Thiol-Ene Chemistry
Ligand-Directed Tosyl and Acyl Imidazole Chemistry
Bioorthogonal Labeling of Cellular Proteins by Enzymatic and Related Mechanisms
Metal-Mediated Bioconjugation
PART 2: APPLICATIONS
Protein and Antibody Labeling
Activity-Based Protein Profiling
Nucleic Acid Labelling, Ligation, and Modification
Chemoselective Reactions for Glycan Labeling
Chemoselective Attachment of Lipids to Proteins
In Vivo Applications of Bioorthogonal Chemistries
Immobilization of Biomolecular Probes for Arrays and Assay: Critical Aspects of Biointerfaces
Chemical Ligations in the Design of Hydrogel Materials
Nanoparticle Bioconjugates: Materials that Benefit from Chemoselective and Bioorthogonal Ligation Chemistries
Application of Engineered Viral Nanoparticles in Materials and Medicine
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