Preface. Symposium Sponsors. American Peptide Symposia. The Merrifield Award. Vincent du Vigneaud Award. Ralph F. Hirschmann Award in Peptide Chemistry. American Peptide Society Travel Grants. The Bruce W. Erickson Young Investigators' Awards. The ESCOM Awards. Abbreviations. The 1999 Merrifield Award / Rao Makineni Lecture. Young Investigators' MiniSymposium. Synthetic Methodologies (including Large-Scale Synthesis). Solid-Phase Organic Synthesis and Combinatorial Methods. Peptide and Peptidomimetic Therapeutics and Delivery. Design and Folding. Non Globular Proteins: Folding and Function. Transmembrane Peptides and Proteins. Analytical and Biophysical Methods. Enzymes and Enzyme Inhibitors. Targeted Protein and Peptide Engineering. Receptors and Receptor Interactions. Signal Transduction (including G-Protein-Coupled Transmembrane Receptors). Peptide Applications for Biological Systems. Immunological Roles for Peptides (including Vaccine Development). Molecular Mechanisms of Amyloid-Based Diseases. Membrane-Active Peptide Neurotoxins and Antibiotics. Peptide Conjugates (including Glycopeptides and Lipopeptides). Perspectives for the New Millennium. Author and Subject Indexes. Author Index. Subject Index.